The Registration site for the 14th annual NESS meeting is up: http://www.regonline.com/ness2017. Abstracts for posters and oral presentations will be accepted until October 13, 2017.
The Alder lab has a new publication in collaboration with the May and Robinson labs:
Malhotra, K., Modak, A., Nangia, S., Daman, T.H., Gunsel, U. Robinson, V.L., Mokranjac, D., May, E.R., and Alder, N.N. (2017) Cardiolipin mediates membrane and channel interactions of the mitochondrial TIM23 protein import complex receptor Tim50. Science Advances DOI: 10.1126/sciadv.1700532
This year’s North Eastern Structure Symposium (NESS) will be held on October 28, 2017. The topic is “Through the looking glass: Inspecting Biological Processes by Cryo-EM.
Simon White will be joining the SB3 faculty in August. Simon’s research is focused on the mechanism of assembly of RNA viruses.
Prof. Eric May and postdoc Shivangi Nangia will investigate virus infection mechanisms on world’s Fastest supercomputer for biomolecular simulations. Drs. May and Nangia have received an allocation on the Anton2 supercomputer donated to the Pittsburg Supercomputing Center by D.E. Shaw Research. The allocation was granted based upon a competitive application process which involved peer review by a panel convened by the National Research Council. The allocation will allow them to analyze viral protein-membrane interactions over timescales which are not feasible on standard supercomputing environments.
The North East Structural Symposium will be held on October 14 at the UCONN Health campus. The topic is “New Paradigms in Drug Discovery.” For a list of speakers and registration information follow the NESS link at the bottom of the page.
Keifer DZ, Motwani T, Teschke CM, Jarrold MF. (2016) Measurement of the accurate mass of a 50 MDa infectious virus. Rapid Commun Mass Spectrom. 30(17):1957-62. doi: 10.1002/rcm.7673.
Wu W, Leavitt JC, Cheng N, Gilcrease EB, Motwani T, Teschke CM, Casjens SR, Steven AC. (2016) Localization of the Houdinisome (Ejection Proteins) inside the Bacteriophage P22 Virion by Bubblegram Imaging. MBio. 7(4). pii: e01152-16. doi: 10.1128/mBio.01152-16.
UCONN has entered into a three-year agreement with Schrodinger, Inc. to provide unlimited use of their Suite for Molecular and Materials Simulations. The package can be used for drug discovery, atomic-scale simulations, modeling of biologics, and production of molecular graphics.
Instructions on how to access the software can be found at:
Congratulations to Eric May, who was awarded an NIH R35 MIRA grant for early-stage investigators. The title is “Structural Dynamics of Viral Proteins: Computational Investigation of Capsids, Lytic Peptides and Nucleoproteins Under Varying Conditions.”