|Nathan Alder, Professor
Analysis of the structure, function, and biogenesis of membrane proteins using multiple techniques, primarily fluorescence spectroscopy, and employing yeast as a model system; mitochondrial protein trafficking and assembly; high-resolution fluorescence-based mapping of membrane proteins and analysis of conformational dynamics. Alder Lab
|Andrei Alexandrescu, Professor
High-resolution solution NMR of protein structure, folding, dynamics, and association; amyloids; phage/virus and pathogen proteins; unconventional zinc fingers; mitochondria; metabolomics. Alexandrescu Lab
|Eric May, Associate Professor
Research in the May lab is focused on molecular, multi-scale and coarse-grained modeling of biological systems, with particular focus on viruses. Much of our research is related to understanding conformational changes of viral proteins induced by environmental factors or ligand binding. We also have an interest in understanding the mechanical/material properties of biological systems, particularly as it relates to single-molecule experiments and the development of biological nanomaterials. May Lab
|Dylan Murray, Assistant Professor
The Murray lab focuses on a mechanistic, molecular view of how biopolymers assemble functionally and pathologically. We employ a multi-faceted experimental and computational approach centered around magnetic resonance. Current projects include RNA granule formation and aggregation in neurodegenerative disease; intermediate filament assembly and defects associated with cancers and pediatric disorders; and the structure of the plant cell wall with applications for engineering fossil fuel alternatives and drought tolerance.
|Victoria Robinson, Associate Professor
High-resolution determination of protein structures by X-ray crystallography. The goal of my research is to use genetic, biochemical and structural methodologies to study novel families of bacterial GTPases, which are potential targets for antimicrobial development. Robinson Lab
|Carolyn Teschke, Professor
Biochemical, biophysical, and mutational analysis of virus assembly, especially of the thermodynamics of capsid assembly and maturation reactions.
- The role of the two SecA homologs in protein export in Mycobacterium tuberculosis.
- Protein folding in vivo and in vitro. Interaction of folding intermediates with molecular chaperones.