Nathan Alder
Professor; PhD
Alder Lab Research
Analysis of the structure, function, and biogenesis of membrane proteins using multiple techniques, primarily fluorescence spectroscopy, and employing yeast as a model system; mitochondrial protein trafficking and assembly; high-resolution fluorescence-based mapping of membrane proteins and analysis of conformational dynamics. Alder Lab
Andrei Alexandrescu
Professor; PhD
Alexandrescu Lab Research
High-resolution solution NMR investigations of protein structure, folding, dynamics, and association; NMR methods to investigate residual structure in protein folding intermediates; conserved folding mechanisms of proteins that share the OB-fold structural motif; evolution of protein structure; structures of neuromuscular junction components; NMR methods to study amyloid fibrils; computational approaches to protein folding. Alexandrescu Lab
Eric May
Associate Professor; PhD, SB3 Program Head
May Lab Research
Research in the May lab is focused on molecular, multi-scale and coarse-grained modeling of biological systems, with particular focus on viruses. Much of our research is related to understanding conformational changes of viral proteins induced by environmental factors or ligand binding. We also have an interest in understanding the mechanical/material properties of biological systems, particularly as it relates to single-molecule experiments and the development of biological nanomaterials. May Lab
Victoria Robinson
Associate Professor; PhD and Associate Head of Graduate Research and Education
Robinson Lab Research
High-resolution determination of protein structures by X-ray crystallography. The goal of my research is to use genetic, biochemical and structural methodologies to study novel families of bacterial GTPases, which are potential targets for antimicrobial development. Robinson Lab
Carolyn Teschke
Professor; PhD and Molecular and Cell Biology Department Head
Teschke Lab Research
Biochemical, biophysical, and mutational analysis of virus assembly, especially of the thermodynamics of capsid assembly and maturation reactions.
- The role of the two SecA homologs in protein export in Mycobacterium tuberculosis.
- Protein folding in vivo and in vitro. Interaction of folding intermediates with molecular chaperones.
Teschke Lab
Teaching Faculty:
Chris Malinoski
Assistant Professor In-Residence; PhD
Emeritus Faculty:
Arlene Albert
Professor Emeritus, PhD
Research Interests
The effect of lipids on the structure and function of membrane proteins. Specifically, the structure of the G-protein receptor, rhodopsin, its interaction with lipids and the role which the lipid bilayer composition plays in modulating the biochemistry of visual signal transduction.
James Cole
Professor; PhD
Cole Lab Research
Analysis of macromolecular interactions using analytical ultracentrifugation and multiple biophysical techniques. The systems that we study include the RNA activated protein kinase (PKR); innate immunity antiviral defense pathway; RIG-I-like receptors. Cole Lab